Death by acid rain: VAP or EXIT?

نویسندگان

  • Kentigern Thorburn
  • Andrew Darbyshire
چکیده

Ventilator-associated pneumonia (VAP) is a new (nosocomial) lower respiratory tract infection diagnosed in mechanically ventilated patients 48 or more hours after intubation. There is no gold standard for establishing the diagnosis and its pathogenesis is iatrogenic and multifactorial. Gastro-oesophageal reflux is common in mechanically ventilated children, but its role in VAP remains speculative. VAP is associated with increased mortality and morbidity, prolonged duration of ventilation and hospital stay, and escalated costs of hospitalisation. VAP 'bundles' are championed as the antidote.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Strategies for the Prevention of Ventilator-associated Pneumonia in the Intensive Care Units: A Review

Ventilator-Associated Pneumonia (VAP) accounts for 80%-90% of hospital-acquired pneumonia cases in Intensive Care Units (ICUs). VAP occurs 48-72 hours after intubation, and is observed in 27%-29% of patients with endotracheal tube, and its risk increases with the increase in the duration of mechanical ventilation. In this review study, papers published from 1996-2018 were used to investigate st...

متن کامل

Granulocyte transmigration through the endothelium is regulated by the oxidase activity of vascular adhesion protein-1 (VAP-1).

Polymorphonuclear leukocytes (PMNs) migrate from the blood into areas of inflammation by binding to the endothelial cells of blood vessels via adhesion molecules. Vascular adhesion protein-1 (VAP-1) is one of the molecules mediating leukocyte-endothelial cell interactions. It is also an endothelial cell-surface enzyme (amine oxidase) that produces reactive oxygen species during the catalytic re...

متن کامل

The Effects of Acid Rain on the Fast Plant Brassica Rapa

Introduction This experiment was designed to discover whether or not acid rain stunts the growth of the fast plant brassica rappa. When pollution from various sources combines with moisture in the atmosphere, it falls back to earth as acid rain. Acid rain pollutes lakes, damages trees and wildlife, and washes nutrients out of the soil. Data collected from the early 1960's from New Hampshire's H...

متن کامل

Does Re-intubation Increased Risk of Ventilator- Associated Pneumonia (VAP) in Pediatric Intensive Care Unit Patients?

Introduction:ventilator- associated pneumonia(VAP),as defined by the centers for disease control and prevention (CDC),is a pneumonia that occurs in a patient receiving mechanical ventilation that develops 48 hours or more after initiation of ventilation.re-intubation which occur within 72 hours of planned extubation may effect VAP incidence.the aim of this study was to determine VAP incidence i...

متن کامل

اثر باران اسیدی بر پاسخ های رشدی و فیزیولوژیکی گندم

Acid rain, which is a wet form of gaseous air pollutants, is formed when air pollutants such as SO2, NO2, CO2 in the atmosphere combine with water vapor of clouds. With the increase of concentration of these pollutants, the amount of acid rain increases. Acid rain, which is the mixture of sulphuric, nitric and carbonic acids, results in some changes in the soil such as decrease in pH, uncommon ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 13  شماره 

صفحات  -

تاریخ انتشار 2009